武汉大学中南医院循证与医学转化中心

导航
首页 > 成果展示 > 正文

Oral sex and risk of oral cancer: a meta-analysis of observational studies

发布于2015-06-27 14:40:13    人阅读
作者团队:李胜,曾宪涛,徐畅,张超,王行环,等

Abstract

OBJECTIVE:

Association between oral sex and oral cancer is a highlighted topic all the time; however, many published epidemiological studies remain failed to obtain a consistent conclusion. We performed this meta-analysis to ascertain whether oral sex is a risk factor or a risk marker for oral cancer.

METHOD:

The PubMed database was searched up to August 30, 2013 (latest updated on December 21, 2014) for relevant observational studies that tested the association between oral sex and oral cancer risk. After data extraction from eligible studies, the meta-analysis was conducted using the Comprehensive Meta-Analysis software.

RESULTS:

Finally yielded six case-control studies and one cross-sectional study with 5553 individuals. The results based on random-effects model indicated that there was no significant association between oral sex and risk of oral cancer (odds ratio = 1.15, 95% confidence interval = 0.86-1.54; P = 0.33). Sensitivity analysis showed that the result was robust and subgroups analyses also revealed similar results. Publication bias was not detected.

CONCLUSION:

Current evidence suggests that oral sex is a risk marker rather than an independent risk factor for oral cancer. However, the practitioners should assure they are without sexually transmitted diseases and with good oral health, and at least cleaned carefully and thoroughly before oral sex. This article is protected by copyright. All rights reserved.

This article is protected by copyright. All rights reserved.

KEYWORDS:

Meta‐analysis, Oral cancer; Oral cavity cancer; Oral sex; Oropharyngeal cancer; Sexual practices

PMID:26107371 [PubMed - as supplied by publisher]


版权所有:武汉大学中南医院循证与转化医学中心
技术支持:西安渔夫网络科技有限公司
联系我们

湖北省武汉市武昌区,东湖路169号    邮编:430071

电话/传真:+86 027 67812817    邮箱:zhongnan@163.com    微博:http://weibo.com/whuznyy